Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis

Gai Ge; Zhiya Yang; Dongmei Li; G Sybren de Hoog; Dongmei Shi

doi:10.1016/j.mmcr.2019.04.005

Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis

Med Mycol Case Rep. 2019 Apr 16:24:48-50. doi: 10.1016/j.mmcr.2019.04.005. eCollection 2019 Jun.

Authors

Gai Ge¹, Zhiya Yang², Dongmei Li³, G Sybren de Hoog⁴, Dongmei Shi^{2

5}

Affiliations

¹ Jining Medical University, Jining, Shandong, PR China.
² Laboratory of Medical Mycology, Jining NO.1 People's Hospital, Jining, Shandong, PR China.
³ Georgetown University Medical Center, Washington D.C., USA.
⁴ CBS-KNAW Fungal Biodiversity Centre, Utrecht, the Netherlands.
⁵ Department of Dermatology, Jining NO.1 People's Hospital, Jining, Shandong, PR China.

Abstract

Candida parapsilosis (C. parapsilosis) has become a common pathogen, especially in immunocompromised hosts. Here, we present an immunocompetent adult with greenish-black discoloration of the right first finger nail in combination with recurrent onycholysis. C. parapsilosis was isolated from the right first finger nail and was confirmed by morphological characteristics as well as by DNA molecular analysis. Patient was successfully treated with oral itraconazole in a regimen of 5 cycles of 200 mg twice daily for one week, followed by an interruption of treatment for 3 weeks. To our knowledge, this is the first report of C. parapsilosis-induced onychomycosis with recurrent onycholysis.

Keywords: Candida parapsilosis; Discoloration; Onycholysis; Onychomycosis.

Publication types

Case Reports