BCG-induced discitis and osteomyelitis in a patient with a history of bladder cancer

Cheryl L Heck; Gary T Schwartzbauer

doi:10.1097/01.JAA.0000554739.16558.26

BCG-induced discitis and osteomyelitis in a patient with a history of bladder cancer

JAAPA. 2019 May;32(5):1-4. doi: 10.1097/01.JAA.0000554739.16558.26.

Authors

Cheryl L Heck¹, Gary T Schwartzbauer

Affiliation

¹ At the time this article was written, Cheryl L. Heck practiced neurosurgery at St. Agnes Hospital in Baltimore, Md. She now practices physical medicine and rehabilitation at Wellspring Clinic in Bel Air, Md. Gary T. Schwartzbauer practices trauma neurosurgery at the University of Maryland Medical Center's R Adams Cowley Shock Trauma Center in Baltimore. The authors have disclosed no potential conflicts of interest, financial or otherwise.

PMID: 31033722
DOI: 10.1097/01.JAA.0000554739.16558.26

Abstract

This article describes the diagnosis and treatment of a patient with lumbar discitis and osteomyelitis caused by Bacillus Calmette-Guérin instillation therapy for treatment of superficial bladder cancer. Treatment of this rare condition consists of antituberculosis microbial therapy and one or more IV antibiotics to cover multidrug-resistant bacteria in the bone.

Publication types

Case Reports

MeSH terms

Adjuvants, Immunologic / administration & dosage*
Adjuvants, Immunologic / adverse effects*
Administration, Intravesical
Aged, 80 and over
Anti-Bacterial Agents / administration & dosage
BCG Vaccine / administration & dosage*
BCG Vaccine / adverse effects*
Back Pain / etiology
Discitis / chemically induced*
Discitis / diagnostic imaging*
Discitis / drug therapy
Drug Therapy, Combination
Humans
Lumbar Vertebrae / diagnostic imaging*
Magnetic Resonance Imaging
Male
Osteomyelitis / chemically induced*
Osteomyelitis / diagnostic imaging*
Osteomyelitis / drug therapy
Tomography, X-Ray Computed
Treatment Outcome
Urinary Bladder Neoplasms / drug therapy*

Substances

Adjuvants, Immunologic
Anti-Bacterial Agents
BCG Vaccine