Clinical Applications Targeting Periostin

Adv Exp Med Biol. 2019:1132:207-210. doi: 10.1007/978-981-13-6657-4_19.

Abstract

Since periostin is expressed and functioned in incredible diseases , clinical applications have been initiated to directly target periostin for inhibition or activation, or periostin expression is utilized to indicate the disease state or a marker for curing diseases, which will provide novel methods in clinical applications.

Keywords: Biomaterials; Capsular contraction; Clinical application; DNA aptamer; Incredible disease; Lebrikizumab; Osteoporosis; Periostin antibody; RNAi.

Publication types

  • Review

MeSH terms

  • Biomarkers
  • Cell Adhesion Molecules / physiology*
  • Disease
  • Humans
  • Molecular Targeted Therapy*

Substances

  • Biomarkers
  • Cell Adhesion Molecules
  • POSTN protein, human