A fluorinated aza-BODIPY derivative for NIR fluorescence/PA/19F MR tri-modality in vivo imaging

Chem Commun (Camb). 2019 May 21;55(42):5851-5854. doi: 10.1039/c9cc01253b.

Abstract

A fluorinated aza-BODIPY derivative BDPF was developed as a small molecule contrast agent, which displayed highly efficient near infrared fluorescence/photoacoustic/19F MR tri-modality tumor imaging.

MeSH terms

  • A549 Cells
  • Animals
  • Boron Compounds / chemistry*
  • Contrast Media / administration & dosage*
  • Fluorescence
  • Fluorescent Dyes / chemistry*
  • Halogenation
  • Heterografts
  • Humans
  • Hydrogen-Ion Concentration
  • Magnetic Resonance Imaging / methods*
  • Mice
  • Neoplasms / diagnostic imaging*
  • Photoacoustic Techniques / methods*
  • Spectroscopy, Near-Infrared / methods*

Substances

  • Boron Compounds
  • Contrast Media
  • Fluorescent Dyes
  • azaBDPBA compound