Acetylcholine-responsive cargo release using acetylcholinesterase-capped nanomaterials

Tania M Godoy-Reyes; Antoni Llopis-Lorente; Alba García-Fernández; Pablo Gaviña; Ana M Costero; Ramón Martínez-Máñez; Félix Sancenón

doi:10.1039/c9cc02602a

Acetylcholine-responsive cargo release using acetylcholinesterase-capped nanomaterials

Chem Commun (Camb). 2019 May 16;55(41):5785-5788. doi: 10.1039/c9cc02602a.

Authors

Tania M Godoy-Reyes¹, Antoni Llopis-Lorente, Alba García-Fernández, Pablo Gaviña, Ana M Costero, Ramón Martínez-Máñez, Félix Sancenón

Affiliation

¹ Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politécnica de Valencia, Universitat de València, Spain.

PMID: 31041959
DOI: 10.1039/c9cc02602a

Abstract

Mesoporous silica nanoparticles capped with acetylcholinesterase, through boronic ester linkages, selectively release an entrapped cargo in the presence of acetylcholine.