Outcomes of patients with large B-cell lymphomas and progressive disease following CD19-specific CAR T-cell therapy

Victor A Chow; Ajay K Gopal; David G Maloney; Cameron J Turtle; Stephen D Smith; Chaitra S Ujjani; Mazyar Shadman; Ryan D Cassaday; Brian G Till; Yolanda D Tseng; Edus H Warren; Andrei R Shustov; Manoj P Menon; Sandra Bhark; Utkarsh H Acharya; Erin Mullane; Lindsay M Hannan; Jenna M Voutsinas; Ted A Gooley; Ryan C Lynch

doi:10.1002/ajh.25505

Outcomes of patients with large B-cell lymphomas and progressive disease following CD19-specific CAR T-cell therapy

Am J Hematol. 2019 Aug;94(8):E209-E213. doi: 10.1002/ajh.25505. Epub 2019 May 21.

Authors

Victor A Chow^{1

2

3}, Ajay K Gopal^{1

2

3}, David G Maloney^{1

2

3}, Cameron J Turtle^{1

2

3}, Stephen D Smith^{1

2

3}, Chaitra S Ujjani^{1

2

3}, Mazyar Shadman^{1

2

3}, Ryan D Cassaday^{1

2

4}, Brian G Till^{1

2

3}, Yolanda D Tseng^{2

5}, Edus H Warren^{1

2

3}, Andrei R Shustov^{1

2

4}, Manoj P Menon^{1

4}, Sandra Bhark^{2

6}, Utkarsh H Acharya^{1

2

3

7}, Erin Mullane², Lindsay M Hannan^{1

2

3}, Jenna M Voutsinas⁸, Ted A Gooley^{1

8}, Ryan C Lynch^{1

2

3}

Affiliations

¹ Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
² Seattle Cancer Care Alliance, Seattle, Washington.
³ Department of Medicine, Division of Medical Oncology, University of Washington, Seattle, Washington.
⁴ Department of Medicine, Division of Hematology, University of Washington, Seattle, Washington.
⁵ Department of Radiation Oncology, University of Washington, Seattle, Washington.
⁶ Fred Hutchinson Cancer Research Center, Public Health Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
⁷ Department of Medical Oncology, Divisions of Hematologic Malignancies and Cellular Therapy, Dana Farber Cancer Institute, Boston, Massachusetts.
⁸ Swedish Cancer Institute, Seattle, Washington.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural

MeSH terms

Antigens, CD19 / immunology*
Clinical Trials as Topic
Disease Progression
Female
Humans
Immunotherapy / methods*
Kaplan-Meier Estimate
Lymphoma, Large B-Cell, Diffuse / immunology
Lymphoma, Large B-Cell, Diffuse / therapy*
Male
Middle Aged
Receptors, Chimeric Antigen / immunology*
T-Lymphocytes / immunology
T-Lymphocytes / transplantation*

Substances

Antigens, CD19
Receptors, Chimeric Antigen

Publication types

MeSH terms

Substances

Grants and funding