Impacts of CD40- and CD86-Silenced Antigen-Specific B Cells on the Control of Allergies

Am J Rhinol Allergy. 2019 Sep;33(5):513-523. doi: 10.1177/1945892419848188. Epub 2019 May 8.
No abstract available

Keywords: B cell; CD40; CD86; allergy; siRNA.

MeSH terms

  • Animals
  • Antigens, Plant / immunology
  • B-Lymphocytes / immunology*
  • B-Lymphocytes / transplantation*
  • B7-2 Antigen / deficiency
  • B7-2 Antigen / genetics*
  • CD40 Antigens / deficiency
  • CD40 Antigens / genetics*
  • Dendritic Cells / immunology
  • Dendritic Cells / transplantation
  • Gene Silencing
  • Hypersensitivity / prevention & control
  • Hypersensitivity / therapy*
  • Immunization
  • Immunoglobulin E / blood
  • Immunoglobulin E / immunology
  • Interleukin-4 / metabolism
  • Interleukin-5 / metabolism
  • Male
  • Mice
  • Mice, Inbred BALB C
  • Nasal Mucosa / immunology
  • Ovalbumin / immunology
  • Plant Proteins / immunology
  • Rhinitis, Allergic / chemically induced
  • Rhinitis, Allergic / prevention & control
  • Rhinitis, Allergic / therapy

Substances

  • Antigens, Plant
  • B7-2 Antigen
  • CD40 Antigens
  • Cd86 protein, mouse
  • Cry j I protein, Cryptomeria japonica
  • Interleukin-5
  • Plant Proteins
  • Interleukin-4
  • Immunoglobulin E
  • Ovalbumin