Cytomegalovirus Retinitis during Maintenance Therapy in child with Acute Lymphoblastic Leukemia

M S Shah; A A Rahman; M Begum; C H Kibria; F Begum

Cytomegalovirus Retinitis during Maintenance Therapy in child with Acute Lymphoblastic Leukemia

Mymensingh Med J. 2019 Apr;28(2):465-469.

Authors

M S Shah¹, A A Rahman, M Begum, C H Kibria, F Begum

Affiliation

¹ Dr Md Salahuddin Shah, Associate Professor, Department of Haematology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail: shah.fcps@ gmail.com.

PMID: 31086168

Abstract

We report three cases of acute lymphoblastic leukemia (ALL) those were suffered from cytomegalovirus retinitis (CMVR) during maintenance phase therapy. Ophthalmologic examination for loss of vision prompted diagnosis of cytomegalovirus retinitis. Administration of anticytomegalovirus drugs led to complete regression of active retinitis. CMVR should be in mind for children with ALL on maintenance of medical aid, even in those without hematopoietic stem cell transplantation state.

Publication types

Case Reports

MeSH terms

Acute Disease
Antineoplastic Agents / adverse effects
Antiviral Agents / administration & dosage
Antiviral Agents / therapeutic use
Child
Cytomegalovirus
Cytomegalovirus Retinitis / diagnosis*
Cytomegalovirus Retinitis / drug therapy
Cytomegalovirus Retinitis / virology
Eye / virology*
Humans
Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
Visual Acuity

Substances

Antineoplastic Agents
Antiviral Agents