51-year old man with tingling, burning and progressive limb weakness

Pract Neurol. 2018 Oct;18(5):382-388. doi: 10.1136/practneurol-2017-001877. Epub 2018 May 14.

Abstract

Peripheral neuropathy is a common reason for referral to neurology. Chronic acquired demyelinating neuropathies are an important and varied group with overlapping presentations, and may have an immune-mediated cause. Their correct diagnosis is important as they respond to different treatments; timely intervention can prevent irreversible axonal degeneration. We present a case that highlights the approach to an adult presenting with a chronic demyelinating neuropathy.

Keywords: CIDP; POEMS syndrome; Polyneuropathy; castleman’s disease; plasma cell dyscrasia.

Publication types

  • Case Reports
  • Clinical Conference

MeSH terms

  • Castleman Disease / complications*
  • Castleman Disease / diagnostic imaging*
  • Diagnosis, Differential
  • Humans
  • Male
  • Middle Aged
  • Muscle Weakness / complications*
  • Muscle Weakness / diagnostic imaging*
  • POEMS Syndrome / complications*
  • POEMS Syndrome / diagnostic imaging*
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / complications
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / diagnostic imaging