A tocotrienol quinone dimer and xanthones from the leaf extract of Garcinia nigrolineata

Achara Raksat; Wisanu Maneerat; Raymond J Andersen; Stephen G Pyne; Surat Laphookhieo

doi:10.1016/j.fitote.2019.104175

A tocotrienol quinone dimer and xanthones from the leaf extract of Garcinia nigrolineata

Fitoterapia. 2019 Jul:136:104175. doi: 10.1016/j.fitote.2019.104175. Epub 2019 May 13.

Authors

Achara Raksat¹, Wisanu Maneerat¹, Raymond J Andersen², Stephen G Pyne³, Surat Laphookhieo⁴

Affiliations

¹ Center of Chemical Innovation for Sustainability (CIS), Mae Fah Luang University, Chiang Rai 57100, Thailand; School of Science, Mae Fah Luang University, Chiang Rai 57100, Thailand.
² Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada; Department of Earth, Ocean & Atmospheric Sciences, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada.
³ School of Chemistry and Molecular Biosciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.
⁴ Center of Chemical Innovation for Sustainability (CIS), Mae Fah Luang University, Chiang Rai 57100, Thailand; School of Science, Mae Fah Luang University, Chiang Rai 57100, Thailand. Electronic address: [email protected].

PMID: 31095982
DOI: 10.1016/j.fitote.2019.104175

Abstract

Four new compounds (1-4) together with six known compounds (5-10) were isolated from the leaf extract of Garcinia nigrolineata. Compound 4 is a rare tocotrienol quinone dimer. The structures were elucidated based on NMR and MS data. All isolated compounds were evaluated for their antibacterial activities.

Keywords: Antibacterial activities; Garcinia nigrolineata; Tocotrienol; Xanthone.

MeSH terms

Garcinia / chemistry*
Microbial Sensitivity Tests
Molecular Structure
Phytochemicals / isolation & purification
Phytochemicals / pharmacology
Plant Extracts / chemistry*
Plant Leaves / chemistry*
Thailand
Tocotrienols / isolation & purification
Tocotrienols / pharmacology*

Substances

Phytochemicals
Plant Extracts
Tocotrienols