Facile sonochemical synthesis of perovskite-type SrTiO3 nanocubes with reduced graphene oxide nanocatalyst for an enhanced electrochemical detection of α-amino acid (tryptophan)

Mani Govindasamy; Sea-Fue Wang; Wei Chih Pan; Bowya Subramanian; R Jothi Ramalingam; Hamad Al-Lohedan

doi:10.1016/j.ultsonch.2019.04.004

Facile sonochemical synthesis of perovskite-type SrTiO₃ nanocubes with reduced graphene oxide nanocatalyst for an enhanced electrochemical detection of α-amino acid (tryptophan)

Ultrason Sonochem. 2019 Sep:56:193-199. doi: 10.1016/j.ultsonch.2019.04.004. Epub 2019 Apr 13.

Authors

Mani Govindasamy¹, Sea-Fue Wang², Wei Chih Pan¹, Bowya Subramanian³, R Jothi Ramalingam⁴, Hamad Al-Lohedan⁵

Affiliations

¹ Department of Materials and Mineral Resources Engineering, National Taipei University of Technology, No. 1, Sec. 3, Chung-Hsiao East Rd., Taipei 106, Taiwan.
² Department of Materials and Mineral Resources Engineering, National Taipei University of Technology, No. 1, Sec. 3, Chung-Hsiao East Rd., Taipei 106, Taiwan. Electronic address: [email protected].
³ Department of Electrical Engineering and Computer Science, National Taipei University of Technology, No.1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan; Department of Information Technology, KSR College of Engineering, Tiruchengode, Tamil Nadu, India.
⁴ Surfactant Research Chair, Chemistry Department, College of Science, King Saud University, P.O. Box-2455, Riyadh 11451, Saudi Arabia. Electronic address: [email protected].
⁵ Surfactant Research Chair, Chemistry Department, College of Science, King Saud University, P.O. Box-2455, Riyadh 11451, Saudi Arabia.

PMID: 31101255
DOI: 10.1016/j.ultsonch.2019.04.004

Abstract

In this paper, perovskite-type SrTiO₃ nanocubes decorated reduced graphene oxide is synthesized by sonochemical method. The as-synthesized SrTiO₃@RGO nanocomposite was confirmed by XRD, TEM, SEM, elemental mapping and electrochemical technique. Furthermore, surface morphological and X-ray diffraction studies revealed the formation and high loading of SrTiO₃ nanocubes on reduced graphene oxide matrix. The SrTiO₃@RGO nanocomposite modified electrode shows an excellent electrochemical detection towards of amino acid (tryptophan). The developed sensor was showed a wide linear range from 30 nM to 917.3 µM and detection limit is 7.15 nM. Furthermore, the sensitivity was calculated to be 9.11 µA µM^-1 cm². In addition, the proposed modified sensor is exhibited good selectivity, stability, reproducibility and repeatability. The SrTiO₃@RGO catalyst modified electrode was successfully applied to tryptophan analysis in biological samples.

Keywords: Amino acid detection; Electrochemical sensor; Perovskite-type SrTiO(3); Reduced graphene oxide; Sonochemical synthesis.