The purpose of this article is to determine the jurisdictional nature of the conclusions of medical and social expert commissions and military medical commissions in disputes over their appeal by state authorities (using the example of the Ministry of Defense of Ukraine). More than 350 decisions of administrative courts of various instances, medical commissions, as well as medical legislation regulating the activities of medical social expert and military medical commissions, and the procedure for conducting medical, social and military medical examinations, became the material for this study. The methodological basis of this work was the method of empirical analysis judicial practice, which allowed autors to identify and analyze court decisions, as well as methods of legal analysis, systematization and synthesis of medical legislation and others. The concept of this article is based on the use of a single methodological approach - positivism. The main result of the work was the scientific substantiation of the administrative-legal nature of the conclusions of the medical-social expert and the military-medical commissions. The article notes that the conclusions of these medical institutions are aimed at ensuring the implementation of state policy in the field of rehabilitation of persons with disabilities, the creation of legal, economic, political, social, social and psychological conditions to meet their needs in restoring health, material support, feasible labor and public activities, by their nature are public in nature and are subject to appeal in administrative proceedings. The legal status of medical-social expert and military-medical commissions in controversial legal relations in understanding the provisions of the administrative procedural law defines these medical institutions as subjects of authority, has been substantiated. The legal disputes between the Ministry of Defense of Ukraine as the central executive body and the military-medical commissions should be resolved out of court, including through measures of state coercion, it is noted.