Dynamic Neural Representations: An Inferential Challenge for fMRI

Avniel Singh Ghuman; Alex Martin

doi:10.1016/j.tics.2019.04.004

Dynamic Neural Representations: An Inferential Challenge for fMRI

Trends Cogn Sci. 2019 Jul;23(7):534-536. doi: 10.1016/j.tics.2019.04.004. Epub 2019 May 15.

Authors

Avniel Singh Ghuman¹, Alex Martin²

Affiliations

¹ Department of Neurological Surgery and the Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: [email protected].
² Section on Cognitive Neuropsychology, Laboratory of Brain and Cognition, NIMH, NIH, Bethesda, MD, USA.

Abstract

Measures of brain activity with high temporal resolution have shown that the information represented in a single brain region undergoes dynamic changes on the scale of milliseconds. This dynamic process presents a unique inferential challenge to low temporal resolution neural measures, such as BOLD fMRI. Potential solutions for fMRI requiring further investigation and development are discussed.

Keywords: BOLD; FFA; VWFA; hemodynamic response; neurodynamics.

Publication types

Research Support, N.I.H., Extramural
Research Support, N.I.H., Intramural
Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Brain / diagnostic imaging*
Brain / physiology
Electroencephalography
Functional Neuroimaging*
Humans
Magnetic Resonance Imaging*
Temporal Lobe / physiology
Time Factors

Abstract

Publication types

MeSH terms

Grants and funding