Facile synthesis of highly ordered mesoporous Fe3O4 with ultrasensitive detection of dopamine

Yarong Huang; Yongzhao Zhang; Dandan Liu; Menggang Li; Yongsheng Yu; Weiwei Yang; Haibo Li

doi:10.1016/j.talanta.2019.01.099

Facile synthesis of highly ordered mesoporous Fe₃O₄ with ultrasensitive detection of dopamine

Talanta. 2019 Aug 15:201:511-518. doi: 10.1016/j.talanta.2019.01.099. Epub 2019 Jan 30.

Authors

Yarong Huang¹, Yongzhao Zhang¹, Dandan Liu², Menggang Li³, Yongsheng Yu⁴, Weiwei Yang⁵, Haibo Li⁶

Affiliations

¹ Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education, Jilin Normal University, Changchun 130103, China; MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, Heilongjiang 150001, China.
² Department of Endocrinology, The Eighth Affiliated Hospital, Sun Yat-Sen university, Shenzhen 518033, China.
³ MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, Heilongjiang 150001, China.
⁴ Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education, Jilin Normal University, Changchun 130103, China. Electronic address: [email protected].
⁵ MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, Heilongjiang 150001, China. Electronic address: [email protected].
⁶ Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education, Jilin Normal University, Changchun 130103, China.

PMID: 31122458
DOI: 10.1016/j.talanta.2019.01.099

Abstract

Dopamine (DA) detection is significant for the prevention of unfavorable neuronal illness. However, the detection of DA with low concentration still face tremendous challenges. In this study, highly ordered mesoporous Fe₃O₄ materials were synthesized as a biosensor by using mesoporous silica KIT-6 with different aging temperature as hard template. The ordered mesoporous Fe₃O₄ with high surface area modified glassy carbon electrode shows the high sensitivity for detecting DA. Fe₃O₄-40 mesoporous material modified electrode has the highest catalytic activity to DA with a sensitivity of 0.053 nA nM^-1 and a detection limit of 0.8 nM (S/N = 3). The results indicating that the mesoporous Fe₃O₄ material modified electrode exhibits high sensitivity to determine DA at low levels, which can be used for DA real-time monitoring in neutral biological media.

Keywords: Dopamine detection; Electrochemical biosensor; Hard template; Mesoporous Fe(3)O(4).

MeSH terms

Animals
Biosensing Techniques / instrumentation
Biosensing Techniques / methods*
Carbon / chemistry
Dopamine / analysis*
Electrochemical Techniques / instrumentation
Electrochemical Techniques / methods
Electrodes
Ferrosoferric Oxide / chemical synthesis
Ferrosoferric Oxide / chemistry*
Limit of Detection
PC12 Cells
Porosity
Rats
Silicon Dioxide / chemistry

Substances

Carbon
Silicon Dioxide
Dopamine
Ferrosoferric Oxide