Abstract
Recent findings have renewed interest in antiphospholipid antibodies. The association of lupus anticoagulant with thrombosis, fetal loss, thrombocytopenia and possibly a Coombs' positive test is among these findings. A method to detect anticardiolipin antibodies and the association of these antibodies with the same clinical disorders as the lupus anticoagulant suggest a relationship between these 2 antibodies.
MeSH terms
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Antibodies, Antinuclear / analysis
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Autoantibodies / analysis*
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Blood Coagulation Factors / analysis
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Blood Coagulation Factors / immunology
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Cardiolipins / immunology
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DNA / immunology
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Female
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Fetal Death
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Humans
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Infant, Newborn
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Lupus Coagulation Inhibitor
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Lupus Erythematosus, Systemic / immunology*
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Phospholipids / immunology*
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Pregnancy
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Pregnancy Complications / immunology
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Risk
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Thrombocytopenia / immunology
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Thrombosis / immunology
Substances
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Antibodies, Antinuclear
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Autoantibodies
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Blood Coagulation Factors
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Cardiolipins
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Lupus Coagulation Inhibitor
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Phospholipids
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DNA