Bullous pemphigoid autoantibody-mediated complement fixation is abolished by the low-molecular-weight heparin tinzaparin sodium

Br J Dermatol. 2019 Sep;181(3):593-594. doi: 10.1111/bjd.18156. Epub 2019 Jun 5.
No abstract available

Publication types

  • Letter

MeSH terms

  • Autoantibodies / blood
  • Autoantibodies / immunology
  • Autoantibodies / metabolism*
  • Autoantigens / immunology
  • Collagen Type XVII
  • Complement Activation / drug effects*
  • Complement Activation / immunology
  • Complement C5a / immunology
  • Complement C5a / metabolism*
  • Complement Fixation Tests
  • Dystonin / immunology
  • Humans
  • Non-Fibrillar Collagens / immunology
  • Off-Label Use
  • Pemphigoid, Bullous / blood
  • Pemphigoid, Bullous / drug therapy
  • Pemphigoid, Bullous / immunology*
  • Skin / immunology
  • Skin / pathology
  • Tinzaparin / pharmacology*
  • Tinzaparin / therapeutic use

Substances

  • Autoantibodies
  • Autoantigens
  • DST protein, human
  • Dystonin
  • Non-Fibrillar Collagens
  • Tinzaparin
  • Complement C5a