Use of the vesicular stomatitis virus (VSV)-based Ebola virus vaccine during outbreaks and the potential use of a similar VSV-based Lassa virus vaccine has raised questions about the vaccines' stability should the cold chain fail. We demonstrated that current cold chain conditions might tolerate significant variances without affecting efficacy.
Keywords: Canada; Ebola virus; Lassa virus; Viral hemorrhagic fever; temperature stability; vaccine stability; vaccines; vesicular stomatitis virus; viruses.