Clarifying the role of EMSY in DNA repair in ovarian cancer

Cancer. 2019 Aug 15;125(16):2720-2724. doi: 10.1002/cncr.32135. Epub 2019 Jun 2.

Authors

Olga Kondrashova^{1

2}, Clare L Scott^{1

3

4}

Affiliations

¹ Cancer Biology and Stem Cells Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
² Genetics & Computational Biology Department, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
³ Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
⁴ Royal Women's Hospital, University of Melbourne, Melbourne, Victoria, Australia.

PMID: 31154666
DOI: 10.1002/cncr.32135

No abstract available

Keywords: DNA repair; EMSY amplification; EMSY overexpression; PARP inhibitors; homologous recombination; ovarian cancer.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

DNA Repair / physiology*
Female
Gene Expression Regulation, Neoplastic
Humans
Neoplasm Proteins / genetics*
Nuclear Proteins / genetics*
Ovarian Neoplasms / genetics*
Rad51 Recombinase / genetics
Repressor Proteins / genetics*

Substances

EMSY protein, human
Neoplasm Proteins
Nuclear Proteins
Repressor Proteins
RAD51 protein, human
Rad51 Recombinase