Burosumab Therapy for X-Linked Hypophosphatemia and Therapeutic Implications for CKD

Clin J Am Soc Nephrol. 2019 Jul 5;14(7):1097-1099. doi: 10.2215/CJN.15201218. Epub 2019 Jun 6.
No abstract available

Keywords: CKD; FGF23; Familial Hypophosphatemic Rickets; Genetic Linkage; Hypophosphatemia, Familial; Renal Insufficiency, Chronic; Vitamin D; burosumab; phosphorus; rickets.

MeSH terms

  • Animals
  • Antibodies, Monoclonal / therapeutic use*
  • Antibodies, Monoclonal, Humanized
  • Familial Hypophosphatemic Rickets / drug therapy*
  • Fibroblast Growth Factor-23
  • Fibroblast Growth Factors / antagonists & inhibitors
  • Fibroblast Growth Factors / blood
  • Humans
  • Renal Insufficiency, Chronic / drug therapy*
  • Vitamin D / analogs & derivatives
  • Vitamin D / blood

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • FGF23 protein, human
  • Vitamin D
  • Fibroblast Growth Factors
  • 1,25-dihydroxyvitamin D
  • Fibroblast Growth Factor-23
  • burosumab