A peripheral T-cell lymphoma (PTCL) arising as a post-transplant lymphoproliferative disorder: efficacy of pralatrexate in primary refractory disease and review of the literature

Leuk Lymphoma. 2019 Dec;60(13):3300-3303. doi: 10.1080/10428194.2019.1622102. Epub 2019 Jun 11.

Authors

Helen Ma¹, Govind Bhagat¹, Owen A O'Connor¹

Affiliation

¹ Center for Lymphoid Malignancies, Department of Medicine, and Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.

PMID: 31184235
DOI: 10.1080/10428194.2019.1622102

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't
Review

MeSH terms

Adult
Aminopterin / analogs & derivatives*
Aminopterin / pharmacology
Aminopterin / therapeutic use
Antineoplastic Combined Chemotherapy Protocols / pharmacology
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biomarkers, Tumor / genetics
Cardiomyopathies / surgery
Deoxycytidine / analogs & derivatives
Deoxycytidine / pharmacology
Deoxycytidine / therapeutic use
Drug Resistance, Neoplasm / genetics
Female
Folic Acid Antagonists / pharmacology
Folic Acid Antagonists / therapeutic use*
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Heart Failure / surgery
Heart Transplantation / adverse effects*
Humans
Lymphoma, T-Cell, Peripheral / diagnosis
Lymphoma, T-Cell, Peripheral / drug therapy*
Lymphoma, T-Cell, Peripheral / etiology
Lymphoma, T-Cell, Peripheral / pathology
Organoplatinum Compounds / pharmacology
Organoplatinum Compounds / therapeutic use
Peripartum Period
Positron Emission Tomography Computed Tomography
Postoperative Complications / diagnosis
Postoperative Complications / drug therapy*
Postoperative Complications / etiology
Postoperative Complications / pathology
Treatment Outcome

Substances

10-propargyl-10-deazaaminopterin
Biomarkers, Tumor
Folic Acid Antagonists
Organoplatinum Compounds
Deoxycytidine
Aminopterin

Supplementary concepts

gemcitabine-oxaliplatin regimen