Case report of parathyroid carcinoma in a pediatric patient

Int J Pediatr Otorhinolaryngol. 2019 Sep:124:120-123. doi: 10.1016/j.ijporl.2019.06.003. Epub 2019 Jun 5.

Abstract

Parathyroid carcinoma is extremely rare in pediatric population. The authors report a case of 15-year-old girl with extremely elevated serum calcium (4.1 mmol/L) and parathyroid hormone (1170 pg/mL), with palpable neck mass. After en bloc resection, the patient remained normocalcemic within the next 2 years. To the best of our knowledge, this is the fourteenth documented case of parathyroid carcinoma in patients younger than 16 years. Even though parathyroid carcinoma is very uncommon in children with good prognosis, this diagnosis has to be considered when a child has severe hypercalcemia, elevated parathyroid hormone and palpable neck mass.

Keywords: Children; En bloc resection; Parathyroid carcinoma; Primary hyperparathyroidism.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Age Factors
  • Female
  • Humans
  • Hypercalcemia / etiology
  • Parathyroid Hormone / blood
  • Parathyroid Neoplasms / diagnosis*
  • Parathyroid Neoplasms / surgery*

Substances

  • Parathyroid Hormone