Dexfenfluramin: a forgotten cause of aortic stenosis

Acta Cardiol. 2020 Jun;75(3):269-270. doi: 10.1080/00015385.2019.1580857. Epub 2019 Jun 14.

Authors

Marie Christine Malergue¹, Alice Ohanessian², Konstantinos Zannis², Patrick Bruneval³, Pierre Vladimir Ennezat⁴

Affiliations

¹ Department of Cardiology, Institut Cœur Effort Santé, Paris, France.
² Department of Cardiovascular Surgery, Institut Mutualiste Montsouris, Paris, France.
³ Department of Pathology, Hôpital Européen Georges Pompidou, Paris, France.
⁴ Department of Cardiology, Centre Hospitalier Universitaire de Grenoble-Alpes, La Tronche, France.

PMID: 31199198
DOI: 10.1080/00015385.2019.1580857

No abstract available

Keywords: Drug-induced valvular heart disease; aortic stenosis; dexfenfluramin.

Publication types

Case Reports

MeSH terms

Aortic Valve Stenosis* / chemically induced
Aortic Valve Stenosis* / pathology
Aortic Valve Stenosis* / physiopathology
Aortic Valve Stenosis* / surgery
Appetite Depressants / adverse effects
Appetite Depressants / therapeutic use
Chemically-Induced Disorders* / diagnosis
Chemically-Induced Disorders* / etiology
Dexfenfluramine* / adverse effects
Dexfenfluramine* / therapeutic use
Echocardiography, Doppler / methods
Endocardium / pathology*
Exercise Test / methods
Female
Fibrosis
Heart Valve Diseases* / chemically induced
Heart Valve Diseases* / pathology
Heart Valve Diseases* / physiopathology
Heart Valve Prosthesis Implantation / methods
Humans
Middle Aged
Obesity / drug therapy
Tomography, X-Ray Computed / methods

Substances

Appetite Depressants
Dexfenfluramine