Abstract
Electron microscopy demonstrates that mouse lung ILC2 expressing PSGL-1 have platelets attached to their surface and that platelet depletion reduces lung ILC2 proliferation and Th2 cytokines suggesting ILC2 function is influenced by attachment to platelets.
Publication types
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Letter
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Research Support, N.I.H., Extramural
MeSH terms
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Animals
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Blood Platelets / immunology*
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Blood Platelets / metabolism
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Immunity, Innate / immunology*
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Lung / cytology
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Lung / immunology*
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Lymphocytes / immunology*
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Lymphocytes / metabolism
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Membrane Glycoproteins / immunology*
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Membrane Glycoproteins / metabolism
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Mice
Substances
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Membrane Glycoproteins
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P-selectin ligand protein