IFN-γ upregulates membranous and soluble PD-L1 in mesothelioma cells: potential implications for the clinical response to PD-1/PD-L1 blockade

Cell Mol Immunol. 2020 Apr;17(4):410-411. doi: 10.1038/s41423-019-0245-x. Epub 2019 Jun 19.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • B7-H1 Antigen / metabolism*
  • Cell Line, Tumor
  • Cell Membrane / drug effects
  • Cell Membrane / metabolism*
  • Clinical Trials as Topic
  • Humans
  • Immune Checkpoint Inhibitors / pharmacology*
  • Interferon-gamma / pharmacology*
  • Mesothelioma / immunology
  • Solubility
  • Up-Regulation / drug effects*

Substances

  • B7-H1 Antigen
  • Immune Checkpoint Inhibitors
  • Interferon-gamma