Light drives vision by directly activating opsin-based visual pigments in rod and cone photoreceptors. In this issue of Neuron, Morshedian et al. (2019) show that light also drives regeneration of the cone visual pigments via an elegant biochemical mechanism in Müller glial cells of the neural retina that can contribute to sustained cone function under daytime conditions.
Keywords: cones; opsin; photoreceptor retinoid.
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