Comparison of immune system development in nonclinical species and humans: Closing information gaps for immunotoxicity testing and human translatability

Reprod Toxicol. 2019 Oct:89:178-188. doi: 10.1016/j.reprotox.2019.06.005. Epub 2019 Jun 21.

¹ Incyte Corporation, Wilmington, DE, USA. Electronic address: [email protected].
² Charles River Laboratories, Inc., Reno, NV, USA.
³ Pfizer Worldwide Research and Development, Groton, CT, USA.
⁴ AbbVie, Inc. North Chicago, IL, USA.
⁵ Merck and Co., Safety Assessment and Laboratory Animal Resources, West Point, PA, USA.
⁶ Janssen Research & Development, Nonclinical Safety, Spring House, PA, USA.
⁷ Bristol-Myers Squibb Company, Research & Development, New Brunswick, New Jersey, USA.
⁸ Covance Preclinical Services GmbH, Muenster, Germany.

No abstract available

Keywords: Developmental immunotoxicology; Immune system; Immune system development; Immunotoxicology; Nonclinical species.

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