Differential effects of delivery hospital on mortality and morbidity in minority premature and low birth weight neonates

J Perinatol. 2020 Mar;40(3):404-411. doi: 10.1038/s41372-019-0423-9. Epub 2019 Jun 24.

Abstract

Objective: To describe variation in mortality and morbidity effects of high-level, high-volume delivery hospital between racial/ethnic groups and insurance groups.

Study design: Retrospective cohort including infants born at 24-32 weeks gestation or birth weights ≤2500 g in California, Missouri, and Pennsylvania between 1995 and 2009 (n = 636,764). Multivariable logistic random-effects models determined differential effects of birth hospital level/volume on mortality and morbidity through an interaction term between delivery hospital level/volume and either maternal race or insurance status.

Result: Compared to non-Hispanic white neonates, odds of complications of prematurity were 14-25% lower for minority infants in all gestational age and birth weight cohorts delivering at high-level, high-volume centers (odds ratio (ORs) 0.75-0.86, p < 0.001-0.005). Effect size was greatest for Hispanic infants. No difference was noted by insurance status.

Conclusions: Neonates of minority racial/ethnic status derive greater morbidity benefits than non-Hispanic white neonates from delivery at hospitals with high-level, high-volume neonatal intensive care units.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Black or African American
  • Hispanic or Latino
  • Humans
  • Infant
  • Infant Mortality / ethnology*
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Infant, Premature*
  • Infant, Premature, Diseases / ethnology*
  • Infant, Premature, Diseases / mortality
  • Insurance, Health
  • Intensive Care Units, Neonatal / classification
  • Intensive Care Units, Neonatal / statistics & numerical data
  • Minority Groups
  • Retrospective Studies
  • Tertiary Care Centers
  • United States / epidemiology
  • White People