Mulibrey Nanism Syndrome: A Case for Heart Transplantation

Ann Thorac Surg. 2020 Feb;109(2):e115-e117. doi: 10.1016/j.athoracsur.2019.05.021. Epub 2019 Jun 28.

Abstract

Mulibrey nanism syndrome is a rare genetic disorder affecting multiple organ systems. The cardiovascular system is one of the most significantly affected, with simultaneous myocardial and pericardial disease. These patients are usually managed by pericardiectomy to resolve the milieu of hemodynamic problems ensuing due to concurrent constrictive and restrictive pathologies. We highlight the use of cardiac transplantation as a definitive management for a hemodynamically decompensated patient with Mulibrey nanism syndrome.

Publication types

  • Case Reports

MeSH terms

  • Echocardiography
  • Follow-Up Studies
  • Heart Failure / diagnosis
  • Heart Failure / etiology
  • Heart Failure / surgery*
  • Heart Transplantation*
  • Humans
  • Male
  • Mulibrey Nanism / complications*
  • Tomography, X-Ray Computed
  • Young Adult