1 Adam Sharp, MD, PhD, The Institute of Cancer Research; The Royal Marsden, London, United Kingdom; Nuria Porta, PhD; Maryou B.K. Lambros, MPhil; and Jonathan C. Welti, PhD, The Institute of Cancer Research, London, United Kingdom; Alec Paschalis, MD, The Institute of Cancer Research; The Royal Marsden, London, United Kingdom; Ganesh V. Raj, MD, PhD, The University of Texas Southwestern Medical Center, Dallas, TX; Stephen P. Plymate, MD, University of Washington; VA Puget Sound Health Care System Geriatric Research Education and Clinical Center, Seattle, WA; and Johann S. de Bono, MD, PhD, The Institute of Cancer Research; The Royal Marsden, London, United Kingdom.