Successful Treatment of Anal Canal Cancer Metastasis to the Cranial Bones: A Case Report and Literature Review

In Vivo. 2019 Jul-Aug;33(4):1347-1353. doi: 10.21873/invivo.11610.

Abstract

Single metastasis to the cranial bone represents a very uncommon occurrence that can arise from an anal canal cancer. No cases of cranial bone metastasis from anal canal carcinoma are available in the literature. Herein, we present a case of a unique metastatic lesion to the right parietal bone that occurred after curative chemoradiotherapy of primary squamous cell anal canal carcinoma. The patient received radiotherapy and systemic platinum-based chemotherapy, with optimal local control, high compliance and a well tolerable level of toxicity.

Keywords: Anal canal carcinoma; bone metastasis; calvarial; chemotherapy; hypofractionated; radiotherapy; survival.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Anus Neoplasms / pathology*
  • Bone Neoplasms / diagnosis
  • Bone Neoplasms / secondary*
  • Bone Neoplasms / therapy*
  • Combined Modality Therapy
  • Female
  • Humans
  • Radiation Dose Hypofractionation
  • Radiotherapy
  • Skull / pathology*
  • Tomography, X-Ray Computed
  • Treatment Outcome

Supplementary concepts

  • Anal Canal Carcinoma