Abstract
Gold nanostars coated with a mesoporous silica shell and functionalized with poly(ethylene glycol) containing photolabile 2-nitrobenzyl moieties are able to release doxorubicin after NIR light irradiation at low power irradiance via a multiphoton absorption photo-dissociation process.
MeSH terms
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Antineoplastic Agents / pharmacology
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Doxorubicin / pharmacology
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Drug Carriers / chemical synthesis
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Drug Carriers / chemistry*
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Drug Carriers / toxicity
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Drug Liberation
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Gold / chemistry*
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HeLa Cells
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Humans
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Infrared Rays
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Metal Nanoparticles / chemistry*
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Metal Nanoparticles / radiation effects
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Metal Nanoparticles / toxicity
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Nitrobenzenes / chemical synthesis
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Nitrobenzenes / chemistry*
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Nitrobenzenes / radiation effects
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Nitrobenzenes / toxicity
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Polyethylene Glycols / chemical synthesis
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Polyethylene Glycols / chemistry*
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Polyethylene Glycols / toxicity
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Porosity
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Silicon Dioxide / chemistry*
Substances
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Antineoplastic Agents
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Drug Carriers
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Nitrobenzenes
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Polyethylene Glycols
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Gold
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Silicon Dioxide
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Doxorubicin