A comparison of the effects of Buserelin versus danazol on plasma lipoproteins during treatment of pelvic endometriosis

Fertil Steril. 1988 May;49(5):913-6. doi: 10.1016/s0015-0282(16)59906-3.

Abstract

Twelve patients receiving Buserelin and seven patients receiving danazol for treatment of endometriosis were studied to assess the effect of medication on plasma lipoproteins. Danazol significantly lowered plasma HDL-C levels at 6 months of treatment. Total plasma cholesterol was elevated at 6 months of therapy in the Buserelin group. No effect by either drug on plasma triglycerides was seen.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Buserelin / therapeutic use*
  • Cholesterol / blood
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Danazol / therapeutic use*
  • Endometriosis / blood
  • Endometriosis / drug therapy*
  • Female
  • Humans
  • Lipoproteins / blood*
  • Pregnadienes / therapeutic use*

Substances

  • Cholesterol, HDL
  • Cholesterol, LDL
  • Lipoproteins
  • Pregnadienes
  • Cholesterol
  • Danazol
  • Buserelin