The current status of anthelmintic resistance in a temperate region of Australia; implications for small ruminant farm management

Vet Parasitol Reg Stud Reports. 2019 Aug:17:100313. doi: 10.1016/j.vprsr.2019.100313. Epub 2019 Jun 12.

Abstract

Widespread anthelmintic resistance in small ruminants is a constraint on the profitability of the meat/wool industry. Limited published data is available on the prevalence and efficacy of anthelmintics, particularly in Australia where parasites affecting ruminant systems vary greatly between geographic regions. This paper reports on the anthelmintic resistance status in a temperate region of Victoria, Australia, a major sheep producing state largely affected by Trichostrongylus species and Teladorsagia circumcincta. The prevalence of anthelmintic resistance to any product was high (71%), with farms reporting varying levels of drug efficacies (21-100%). Resistance to older chemical groups (i.e. fenbendazole and levamisole) and single active macrocyclic lactone treatments was higher than newer chemical groups and combination treatments. This report provides clarity on anthelmintic resistance in the temperate region of Victoria and more importantly suggests that more comprehensive, regional specific anthelmintic resistance studies are required to understand the real level of chemical resistance threatening the effective control of worms.

Keywords: Anthelmintic resistance; FECRT; Gastrointestinal parasites; Macrocyclic lactones; Small ruminants.

MeSH terms

  • Animal Husbandry / methods*
  • Animal Husbandry / trends
  • Animals
  • Anthelmintics / pharmacology*
  • Anthelmintics / therapeutic use
  • Drug Resistance*
  • Farms / organization & administration
  • Farms / trends
  • Feces / parasitology
  • Female
  • Helminthiasis, Animal / drug therapy
  • Helminthiasis, Animal / epidemiology
  • Helminthiasis, Animal / parasitology*
  • Parasite Egg Count / veterinary
  • Prevalence
  • Sheep
  • Sheep Diseases / drug therapy
  • Sheep Diseases / epidemiology
  • Sheep Diseases / parasitology*
  • Victoria / epidemiology

Substances

  • Anthelmintics