Design and assembly of a chiral composite metal-organic framework for efficient asymmertric sequential transformation of alkenes to amino alcohols

Qingchun Xia; Chen Yuan; Yongxin Li; Yong Cui

doi:10.1039/c9cc04131a

Design and assembly of a chiral composite metal-organic framework for efficient asymmertric sequential transformation of alkenes to amino alcohols

Chem Commun (Camb). 2019 Jul 30;55(62):9136-9139. doi: 10.1039/c9cc04131a.

Authors

Qingchun Xia¹, Chen Yuan, Yongxin Li, Yong Cui

Affiliation

¹ School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China. [email protected].

PMID: 31304488
DOI: 10.1039/c9cc04131a

Abstract

In this work, we report the successful construction of two chiral porous metal-metallosalan frameworks (1 and 2) by using dipyridylfunctionalized chiral Al(salen) and Mn(salen) separately, and then a composite crystal MOF 3 was constructed with 1 inside, which was encapsulated by 2 outside. The resulting composite crystal appeared to be highly enantioselective for the alkene epoxidation/epoxide aminolysis reactions with a maximum ee of 97%.