The negative symptoms and cognitive symptoms of schizophrenia patients are still clinical problems to be solved. Schizophrenia patients are abnormal in oxidative stress, immune regulation, and anti-histone deacetylase (HDAC), while sulforaphane plays a role in anti-oxidative stress, anti-inflammation, and anti-HDAC. Therefore, the sulforaphane could improve the negative symptoms and cognitive deficits of schizophrenia.
精神分裂症患者的阴性症状与认知缺陷的治疗仍然是临床难题。精神分裂症患者存在氧化应激、免疫调节、抗组蛋白去乙酰化酶(histone deacetylase，HDAC)等方面的异常，而萝卜硫素具有抗氧化应激、抗炎、抗HDAC等作用。因此，萝卜硫素可能通过上述作用改善精神分裂症的阴性症状及认知缺陷。.