Splenic marginal zone lymphoma associated with hepatitis B virus infection, remission after viral treatment, and splenectomy: A case report and review of the literature

Mounir Ababou; El Mehdi Mahtat; Selim Jennane; Hicham Elmaaroufi; Mohammed Mikdame; Kamal Doghmi

doi:10.1016/j.hemonc.2019.05.007

Splenic marginal zone lymphoma associated with hepatitis B virus infection, remission after viral treatment, and splenectomy: A case report and review of the literature

Hematol Oncol Stem Cell Ther. 2021 Jun;14(2):153-155. doi: 10.1016/j.hemonc.2019.05.007. Epub 2019 Jul 9.

Authors

Mounir Ababou¹, El Mehdi Mahtat², Selim Jennane², Hicham Elmaaroufi², Mohammed Mikdame², Kamal Doghmi²

Affiliations

¹ Department of Clinical Hematology, Military Hospital Mohammed V, Rabat, Morocco. Electronic address: [email protected].
² Department of Clinical Hematology, Military Hospital Mohammed V, Rabat, Morocco.

PMID: 31306619
DOI: 10.1016/j.hemonc.2019.05.007

Abstract

We report the case of a patient diagnosed with a splenic marginal zone lymphoma with a simultaneous finding of hepatitis B virus infection, who responded to antiviral treatment and splenectomy. We highlighted this association described in the literature and its possible causal role, as well as the available therapeutic choices.

Keywords: Hepatitis B virus (HBV); Splenectomy; Splenic marginal zone lymphoma (SMZL).

Publication types

Case Reports
Review

MeSH terms

Antiviral Agents / therapeutic use
Hepatitis B / complications*
Hepatitis B / therapy
Hepatitis B virus / drug effects
Hepatitis B virus / isolation & purification
Humans
Lymphoma, B-Cell, Marginal Zone / complications*
Lymphoma, B-Cell, Marginal Zone / therapy
Male
Middle Aged
Splenectomy
Splenic Neoplasms / complications*
Splenic Neoplasms / therapy

Substances

Antiviral Agents