Draft genome and description of Chryseobacterium phocaeense sp. nov.: a new bacterial species isolated from the sputum of a cystic fibrosis patient

Arch Microbiol. 2019 Dec;201(10):1361-1368. doi: 10.1007/s00203-019-01704-1. Epub 2019 Jul 22.

Abstract

Strain 6021061333T was isolated from the sputum of 16-year-old girl with cystic fibrosis following a pulmonary exacerbation. This bacterial strain could not be identified by our systematic MALDI-TOF mass spectrometry screening on a MicroFlex. This led to the sequencing of the 16S rRNA gene, which shows 97.83% sequence identity with Chryseobacterium kwangjuense strain KJ1R5T, the phylogenetic closely related type strain of a species with standing in nomenclature, which putatively classifies it as a new species. Colonies are yellow, circular and 0.5-1 mm in diameter after cultivation at 28 °C for 24 h on 5% sheep blood-enriched Colombia agar. Growth occurs at temperatures in the range of 28-37 °C (optimally at 28 °C). Strain 6021061333T is Gram-negative, non-motile and strictly aerobic bacillus. It is catalase and oxidase positive. The 4,864,678 bp-long genome, composed of five contigs, has a G+C content of 38.86%. Out of the 4427 predicted genes, 4342 were protein-coding genes and 85 were RNAs. The major fatty acids are branched (13-methyl-tetradecanoic acid and 15-methyl-hexadecenoic acid). Digital DNA-DNA hybridization (dDDH) estimation and average nucleotide identity (ANI) of the strain 6021061333T against genomes of the type strains of related species ranged between 23.60 and 50.40% and between 79.31 and 93.06%, respectively. According to our taxonogenomics results, we propose the creation of Chryseobacterium phocaeense sp. nov. that contains the type strain 6021061333T (= CSUR P2660, = CECT 9670).

Keywords: Chryseobacterium phocaeense; Cystic fibrosis; Genome; Taxonogenomics.

MeSH terms

  • Adolescent
  • Base Composition
  • Chryseobacterium / chemistry
  • Chryseobacterium / classification*
  • Chryseobacterium / genetics*
  • Cystic Fibrosis / microbiology*
  • DNA, Bacterial / genetics
  • Fatty Acids / analysis
  • Female
  • Genome, Bacterial / genetics
  • Humans
  • Nucleic Acid Hybridization
  • Phylogeny*
  • RNA, Ribosomal, 16S / genetics
  • Sequence Homology, Nucleic Acid
  • Species Specificity
  • Sputum / microbiology

Substances

  • DNA, Bacterial
  • Fatty Acids
  • RNA, Ribosomal, 16S