Data on CXC chemokine ligand 10(CXCL10) expression and activation in red sea bream during bacterial and viral infection

Won-Sik Woo; Min Soo Joo; Jee Youn Hwang; Mun-Gyeong Kwon; Jung Soo Seo; Seong Don Hwang; Bo-Yeong Jee; Mu-Chan Kim; Chan-Il Park

doi:10.1016/j.dib.2019.103943

Data on CXC chemokine ligand 10(CXCL10) expression and activation in red sea bream during bacterial and viral infection

Data Brief. 2019 Apr 23:25:103943. doi: 10.1016/j.dib.2019.103943. eCollection 2019 Aug.

Authors

Won-Sik Woo¹, Min Soo Joo¹, Jee Youn Hwang², Mun-Gyeong Kwon², Jung Soo Seo², Seong Don Hwang², Bo-Yeong Jee², Mu-Chan Kim¹, Chan-Il Park¹

Affiliations

¹ Institute of Marine Industry, College of Marine Science, Gyeongsang National University, 455, Tongyeong 650-160, Republic of Korea.
² Aquatic Animal Disease Control Center, National Institute of Fisheries Science (NIFS), 216 Gijanghaean-ro, Gijang-eup, Gijang-gun, Busan 46083, Republic of Korea.

Abstract

CXCL10 plays an important role in angiogenesis and inhibits the differentiation of endothelial cells into capillaries. It also plays an important role in the generation and transmission of effector T cell responses and the recruitment of T cells to inflammatory sites. In this article, we constructed cDNAs to identify and analyse the CXCL10 domain, and performed multiple alignments and a phylogenetic analysis to determine homology with other animals. Real-time PCR was performed to confirm construction and expression after bacterial and viral infection.