Non-Melanoma Skin Cancers in the Older Patient

Curr Oncol Rep. 2019 Jul 29;21(9):79. doi: 10.1007/s11912-019-0828-9.

Abstract

Purpose of review: The incidence of non-melanomatous skin cancer (NMSC) increases with age and there are specific considerations regarding management of NMSC for the older patient population. Here we will review current data regarding treatment considerations and options for older patients with NMSC.

Recent findings: Hypofractionated regimens and high-dose brachytherapy may be non-surgical treatment options for older patients with NMSC. Other less aggressive strategies such as active surveillance can also be considered in some settings. Management of NMSC in the older patient population requires a thorough assessment of comorbidities, frailty, and life expectancy. Additionally, discussions regarding goals of care and quality of life (QOL) issues are especially important in this population. Older patients with NMSC in particular may benefit from a tailored treatment plan based on current available data rather than a broad application of general treatment guidelines for NMSC.

Keywords: Geriatric oncology; Non-melanoma skin cancer; Radiation therapy; Radiotherapy; Skin cancer; Surgery.

Publication types

  • Review

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Clinical Trials, Phase III as Topic
  • Female
  • Geriatric Assessment / methods*
  • Humans
  • Male
  • Molecular Targeted Therapy / methods
  • Quality of Life
  • Radiotherapy / methods
  • Randomized Controlled Trials as Topic
  • Skin Neoplasms / pathology
  • Skin Neoplasms / therapy*