Antibiotic-loaded ceramic sternum for sternal replacement in a patient with deep sternal wound infection

Interact Cardiovasc Thorac Surg. 2019 Dec 1;29(6):973-975. doi: 10.1093/icvts/ivz182.

Abstract

A 68-year-old man presented with destruction of his sternum after cardiac surgery. Classical management with multiple debridements, vacuum dressings and antibiotics failed. A replacement of his sternum was performed using an antibiotic-loaded porous alumina ceramic sternum. Despite the infected wound, the ceramic sternum did not get infected due to the high antibiotic concentration obtained locally. Two years after the surgery, no relapse occurred and the pulmonary function tests improved.

Keywords: Alumina; Antibiotic loaded; Deep sternal wound infection; Mediastinitis; Pulmonary function tests; Sternum.

Publication types

  • Case Reports
  • Validation Study

MeSH terms

  • Aged
  • Anti-Bacterial Agents / pharmacology*
  • Cardiac Surgical Procedures / adverse effects*
  • Ceramics*
  • Coated Materials, Biocompatible*
  • Humans
  • Male
  • Prosthesis Design
  • Prosthesis Implantation / methods*
  • Sternum / surgery*
  • Surgical Wound Infection / etiology
  • Surgical Wound Infection / surgery*

Substances

  • Anti-Bacterial Agents
  • Coated Materials, Biocompatible