Japan ablation registry: cryoablation in atrioventricular nodal reentrant tachycardia ("JARCANRET study"): results from large multicenter retrospective investigation

J Interv Card Electrophysiol. 2020 Sep;58(3):289-297. doi: 10.1007/s10840-019-00585-0. Epub 2019 Jul 31.

Abstract

Purpose: Cryoenergy has been demonstrated to be a safe alternative to radiofrequency ablation for catheter ablation of atrioventricular nodal reentrant tachycardia (AVNRT). This study aimed to evaluate the safety and efficacy of cryoablation in patients with AVNRT.

Methods: A multicenter retrospective study was performed. Two hundred eighty-three consecutive patients with AVNRT underwent cryoablation. Cryomapping at - 30 °C and - 80 °C was performed to predict cryoablation outcome and ascertain antegrade conduction. Cryoenergy was delivered subsequently at the same spot (cryoablation at - 80 °C) for 240 s.

Results: Ablation procedure was acutely successful in 281 out of 283 patients (99.3%). Of note, 22 patients (10.1%) had transient AV block during the cryoablation, but no injurious effects on AV conduction were provoked during cryomapping. During a follow-up period of 367 ± 35 days, the recurrence rate was 3.9% (11 out of 281). There were no significant differences among the patients with a complete elimination of slow pathway conduction, AH jump without an echo beat, and AH jump with a single echo beat, in terms of the long-term recurrence of AVNRT.

Conclusions: Cryoablation of AVNRT appears to be effective both acutely and during the long-term with a minimal risk of unwanted injuries to the conduction system. It seems to be important to monitor the antegrade conduction during cryoenergy applications, even when cryomapping demonstrates a safe location for cryoablation. The recurrence rate of AVNRT did not differ according to the properties of the residual slow pathway conduction.

Keywords: Atrioventricular nodal reentrant tachycardia; Catheter ablation; Cryoablation; Supraventricular tachycardia.

Publication types

  • Multicenter Study

MeSH terms

  • Catheter Ablation*
  • Cryosurgery*
  • Humans
  • Japan / epidemiology
  • Recurrence
  • Registries
  • Retrospective Studies
  • Risk Factors
  • Tachycardia, Atrioventricular Nodal Reentry* / surgery
  • Treatment Outcome