Autoimmune Biomarkers, Antibodies, and Immunologic Evaluation of the Patient with Fibrotic Lung Disease

Argyris Tzouvelekis; Theodoros Karampitsakos; Evangelos Bouros; Vassilios Tzilas; Stamatis-Nick Liossis; Demosthenes Bouros

doi:10.1016/j.ccm.2019.06.002

Autoimmune Biomarkers, Antibodies, and Immunologic Evaluation of the Patient with Fibrotic Lung Disease

Clin Chest Med. 2019 Sep;40(3):679-691. doi: 10.1016/j.ccm.2019.06.002.

Authors

Argyris Tzouvelekis¹, Theodoros Karampitsakos¹, Evangelos Bouros¹, Vassilios Tzilas¹, Stamatis-Nick Liossis², Demosthenes Bouros³

Affiliations

¹ 1st Academic Department of Respiratory Medicine, Medical School, National and Kapodistrian University of Athens, Hospital for Diseases of the Chest, "Sotiria", Mesogion 152, Athens 11527, Greece.
² Division of Rheumatology, Department of Internal Medicine, Patras University Hospital, University of Patras Medical School, Patras, Rio 26504, Greece.
³ 1st Academic Department of Respiratory Medicine, Medical School, National and Kapodistrian University of Athens, Hospital for Diseases of the Chest, "Sotiria", Mesogion 152, Athens 11527, Greece. Electronic address: [email protected].

PMID: 31376900
DOI: 10.1016/j.ccm.2019.06.002

Abstract

This review summarizes the current state of knowledge on experimental and clinical biomarkers of autoimmunity and aims to highlight important aspects of the immunologic evaluation of a patient with fibrotic lung disease.

Keywords: Autoimmunity; Biomarkers; Chronic lung injury; Connective tissue disorders; Interstitial lung diseases.

Publication types

Review

MeSH terms

Autoimmunity / genetics*
Biomarkers / metabolism*
Fibrosis / immunology*
Humans
Lung Diseases, Interstitial / immunology*

Substances

Biomarkers