Cranioplasty with Titanium Might Be Suitable for Adult Epilepsy Surgery After Subdural Placement Surgery To Avoid Surgical Site Infection

World Neurosurg. 2019 Nov:131:e503-e507. doi: 10.1016/j.wneu.2019.07.201. Epub 2019 Aug 2.

Abstract

Background: The purpose of the present study was to compare the surgical site infection (SSI) rates between resorbable plates and titanium plates used for adult patients with intractable epilepsy who had undergone epilepsy surgery after subdural electrode placement.

Methods: We performed subdural electrode surgery, followed by epilepsy surgery, for 87 adult patients with intractable epilepsy. The epilepsy surgery included 75 focus resections and 12 corpus callosotomies. We compared the SSI rates between patients who had undergone cranioplasty with titanium and resorbable plates after epilepsy surgery.

Results: Of the 87 patients, 43 had undergone cranioplasty with resorbable plates (group A) and 44 had undergone cranioplasty with titanium plates (group B). The frequency of SSI was significantly greater in group A (7 patients; 16.3%) than in group B (1 patient; 2.3%; P = 0.03, Fisher's exact test). Univariate regression analysis also showed a significantly greater infection rate with the resorbable plates (P = 0.024).

Conclusion: For epilepsy surgery of adult patients after subdural electrode placement surgery, the SSI rate for cranioplasty was greater with resorbable plates than with titanium plates.

Keywords: Bioresorbable; Cranioplasty; Epilepsy surgery; Surgical site infection; Titanium.

MeSH terms

  • Absorbable Implants*
  • Adult
  • Bone Plates*
  • Case-Control Studies
  • Drug Resistant Epilepsy / surgery*
  • Electrodes
  • Female
  • Humans
  • Male
  • Middle Aged
  • Plastic Surgery Procedures / instrumentation
  • Plastic Surgery Procedures / methods*
  • Skull / surgery*
  • Subdural Space
  • Surgical Wound Infection / epidemiology*
  • Titanium*
  • Young Adult

Substances

  • Titanium