Application of strain and other echocardiographic parameters in the evaluation of early and long-term clinical outcomes after cardiac surgery revascularization

BMC Cardiovasc Disord. 2019 Aug 5;19(1):189. doi: 10.1186/s12872-019-1162-8.

Abstract

Background: Coronary artery bypass graft (CABG) surgery is an effective therapeutic strategy for coronary heart disease (CHD). Myocardial longitudinal strain echocardiography with 2D speckle tracking could obtain ventricular function with better accuracy and reliability than the left ventricular ejection fraction. The aim of the study was to assess changes in left ventricular function in patients before and after surgical revascularization for a 24-month period of observation, using echocardiography with speckle tracking strain imaging. We searched for echocardiographic predictors of poor early and long-term outcome after CABG.

Methods: We enrolled 69 patients scheduled for elective coronary bypass grafting. Patients were divided into groups based on pre-operative systolic and diastolic parameters, depending on the GLS value and the E' Lat and E/E' value. The correlation between these parameters and early and long-term outcomes was analyzed.

Results: Preoperative EF was preserved in 86, 95% (60) patients. Pre-operative reduced GLS was observed in 73.91% (51) of patients and severely reduced in 31.88% (22). In the first post-operative 6-month period, we observed a significant decrease in the GLS. The GLS was a predictor of early postoperative outcome for intubation time, the inotropes use and length of ICU stay. Diastolic dysfunction was a predictor of the greater inotrope requirements.

Conclusions: Global longitudinal strain and diastolic dysfunction parameters are a good predictors of worse early outcome after CABG.

Keywords: Coronary surgery; Echocardiography; Longitudinal strain.

MeSH terms

  • Aged
  • Cardiotonic Agents / therapeutic use
  • Coronary Artery Bypass* / adverse effects
  • Coronary Artery Bypass* / mortality
  • Coronary Artery Disease / diagnostic imaging
  • Coronary Artery Disease / mortality
  • Coronary Artery Disease / physiopathology
  • Coronary Artery Disease / surgery*
  • Echocardiography, Doppler, Pulsed*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / diagnostic imaging*
  • Postoperative Complications / physiopathology
  • Postoperative Complications / therapy
  • Predictive Value of Tests
  • Progression-Free Survival
  • Prospective Studies
  • Recovery of Function
  • Risk Factors
  • Stroke Volume* / drug effects
  • Time Factors
  • Ventricular Function, Left* / drug effects

Substances

  • Cardiotonic Agents