Photodynamic therapy in a patient with facial angiofibromas due to tuberous sclerosis complex

Photodiagnosis Photodyn Ther. 2019 Dec:28:183-185. doi: 10.1016/j.pdpdt.2019.08.009. Epub 2019 Aug 6.

Abstract

The facial angiofbromas due to tuberous sclerosis complex produced significant social and emotional distress for affected individuals, but there is no specific therapeutic strategy up to now. Herein, we report a case of facial angiofibromas successfully treated by 5-aminolaevulinic acid-mediated photodynamic therapy (ALA-PDT) with no recurrence for 6 years, thus providing a promising therapeutic option.

Keywords: 5-Aminolaevulinic acid-mediated photodynamic therapy (ALA-PDT); Facial angiofibromas; Tuberous sclerosis complex (TSC).

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Aminolevulinic Acid / therapeutic use
  • Angiofibroma / drug therapy*
  • Angiofibroma / etiology*
  • Facial Neoplasms / drug therapy*
  • Humans
  • Male
  • Microwaves / therapeutic use
  • Photochemotherapy / methods*
  • Photosensitizing Agents / therapeutic use
  • Tuberous Sclerosis / complications*

Substances

  • Photosensitizing Agents
  • Aminolevulinic Acid