[Results of surgical revisions for ureteral complications after renal transplantation]

Prog Urol. 2019 Sep;29(10):474-481. doi: 10.1016/j.purol.2019.05.010. Epub 2019 Aug 7.
[Article in French]

Abstract

Objective: To analyze the results of surgical revision for ureteral complication (ureteric stenosis or urinary leakage) after renal transplantation over a period of 10 years.

Materials and methods: We performed a retrospective study on 1313 consecutive kidney transplantations carried out in a University Hospital Center between 2005 and 2014. The data of the patients who developed a ureteral stenosis or a urinary leakage secondary to a renal transplantation were analyzed. Combined organ transplantations (kidney-liver and kidney-pancreas), as well as pediatric transplantations were excluded.

Results: Seventy-six patients (5.8%) had ureteric stenosis or urinary leakage after renal transplantation. Forty-six patients (3.5%) underwent surgical revision: 27 for ureteral stenosis, 19 for urinary leakage. Early success was achieved in 26 patients (56.5%), including 14 ureteric stenosis (51.9%) and 12 urinary leakage (63.2%) (P=0.45). After a complementary endoscopic or surgical treatment, the final success rate was increased to 73.1% (34 patients): 20 ureteric stenosis (74.1%) and 14 urinary leakage (73.7%) (P=0.98). There were 2 graft losses (4.3%) and one death (2.2%). The mean glomerular filtration rate estimated by the MDRD was 44.58mL/min/1.73m2 (±14.7) before surgery and 45.37mL/min/1.73m2 (±16.5) 6 months after surgery (P=0.92).

Conclusion: Although frequently challenging, surgical revisions for ureteral complications after renal transplantation give good results, with a low rate of graft loss and mortality.

Level of evidence: 4.

Keywords: Complication urétérale; Fistule urinaire; Kidney transplantation; Reprise chirurgicale; Sténose urétérale; Surgical revision; Transplantation rénale; Ureteral complication; Ureteric stenosis; Urinary leakage.

MeSH terms

  • Aged
  • Constriction, Pathologic / surgery
  • Female
  • Humans
  • Kidney Transplantation*
  • Male
  • Middle Aged
  • Postoperative Complications / surgery*
  • Reoperation
  • Retrospective Studies
  • Treatment Outcome
  • Ureteral Obstruction / surgery*
  • Urinary Incontinence / surgery*