Evolving Practice Patterns in the Use of Prophylactic Cranial Irradiation for Extensive-Stage Small Cell Lung Cancer

Olsi Gjyshi; Ethan B Ludmir; Todd A Pezzi; David Boyce-Fappiano; Amy E Dursteler; Timur Mitin; Steven H Lin

doi:10.1001/jamanetworkopen.2019.9135

Evolving Practice Patterns in the Use of Prophylactic Cranial Irradiation for Extensive-Stage Small Cell Lung Cancer

JAMA Netw Open. 2019 Aug 2;2(8):e199135. doi: 10.1001/jamanetworkopen.2019.9135.

Authors

Olsi Gjyshi¹, Ethan B Ludmir¹, Todd A Pezzi¹, David Boyce-Fappiano¹, Amy E Dursteler¹, Timur Mitin², Steven H Lin¹

Affiliations

¹ Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston.
² Department of Radiation Medicine, Oregon Health & Science University, Portland.

Abstract

This survey study compares use of prophylactic cranial irradiation in patients with extensive-stage small cell lung cancer before and after the publication of a phase 3 trial that demonstrated no overall survival benefit for this therapy.

MeSH terms

Cranial Irradiation / statistics & numerical data*
Humans
Lung Neoplasms / radiotherapy*
Practice Patterns, Physicians' / statistics & numerical data*
Radiation Oncology / methods
Small Cell Lung Carcinoma / radiotherapy*
Surveys and Questionnaires
United States