The Gut Feeling: GPCRs Enlighten the Way

Shubhi Pandey; Jagannath Maharana; Arun K Shukla

doi:10.1016/j.chom.2019.07.018

The Gut Feeling: GPCRs Enlighten the Way

Cell Host Microbe. 2019 Aug 14;26(2):160-162. doi: 10.1016/j.chom.2019.07.018.

Authors

Shubhi Pandey¹, Jagannath Maharana¹, Arun K Shukla²

Affiliations

¹ Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.
² Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India. Electronic address: [email protected].

Abstract

Host-microbiome interactions affect host physiology, but the underlying mechanisms are not well understood. Recent papers from Chen et al. (2019) and Colosimo et al. (2019) in this issue of Cell Host & Microbe demonstrate that metabolites produced by several members of the gut microbiota can efficiently activate host G protein-coupled receptors and influence host physiology.

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MeSH terms

Bacteria
Humans
Ligands
Microbiota*
Receptors, G-Protein-Coupled*
Signal Transduction

Substances

Ligands
Receptors, G-Protein-Coupled

Abstract

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MeSH terms

Substances

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