Abstract
Eleven patients having a selective IgA deficiency had very low T-cell percentages assessed by using E-rosettes, active E-rosetts and an anti-human anti-T-lymphocyte antigen serum. B-cells were normal or slightly decreased. IgE concentrations were often low. Patients with serum IgA under 50 IU/ml often had elevated serum IgE values and low T-cell percentages. Serum thymic factor dosages were correlated with the E-rosette assay.
MeSH terms
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Adolescent
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Adult
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Agammaglobulinemia / immunology*
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Aged
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Antilymphocyte Serum / pharmacology
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B-Lymphocytes / immunology
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Child
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Humans
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Immunoglobulin A*
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Immunoglobulin A, Secretory
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Immunoglobulin E* / immunology*
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Immunoglobulin Fc Fragments
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Immunoglobulin G
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Immunoglobulin M
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Lymphocytes / immunology*
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Middle Aged
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Rosette Formation
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T-Lymphocytes / immunology*
Substances
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Antilymphocyte Serum
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Immunoglobulin A
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Immunoglobulin A, Secretory
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Immunoglobulin Fc Fragments
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Immunoglobulin G
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Immunoglobulin M
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Immunoglobulin E