Factors influencing the perception of protective isolation in patients undergoing haematopoietic stem cell transplantation: A multicentre prospective study

Eur J Cancer Care (Engl). 2019 Nov;28(6):e13148. doi: 10.1111/ecc.13148. Epub 2019 Aug 20.

Abstract

Objectives: To identify which factors can influence the patients' perception of protective isolation following Haematopoietic Stem Cell Transplantation (HSCT).

Methods: This is a prospective study conducted in 10 Italian centres, members of the Italian Group of stem cell transplant (GITMO). Patients' perception of protective isolation was assessed using the ISOLA scale between 7 and 9 days post-transplant. Statistical linear regression analysis was performed.

Results: The participants were 182 adult patients receiving autologous (48%) or allogeneic (52%) HSCT in protective isolation. Male sex (β = .152), education level (β = -.245), double room (β = .186), satisfaction with visiting hours (β = -.174) and emotional support from nurses (β = -.169) were independently associated with isolation-related suffering. Significant predictors of the relationship with oneself included body temperature (β = -.179), fatigue (β = -.192) and emotional support from nurses (β = -.292). Factors independently associated with the relationship with others were education (β = -.230), chemotherapy cycles (β = -.218), pain (β = .150) and satisfaction with visiting hours (β = -.162).

Conclusion: Healthcare providers should pay greater attention in caring for those patients who are at risk for a negative isolation experience. Nurses should provide emotional support.

Keywords: haematopoietic stem cell transplantation; hospitalisation; loneliness; patient isolation; risk factors.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Attitude to Health*
  • Female
  • Hematologic Neoplasms / psychology
  • Hematologic Neoplasms / therapy
  • Hematopoietic Stem Cell Transplantation / psychology*
  • Humans
  • Italy
  • Linear Models
  • Male
  • Middle Aged
  • Patient Isolation / psychology*
  • Perception
  • Prospective Studies
  • Surveys and Questionnaires
  • Transplantation, Autologous / psychology
  • Transplantation, Homologous / psychology
  • Young Adult